Neurotoxicity is a significant tumor-and treatment-related complication for a number of childhood cancer survivors. It is particularly relevant for children with brain tumors who require therapy specifically directed at the central nervous system. Despite its significance, relatively little is known about the etiology, diagnosis, prevention, or treatment of neurotoxicity. As…
Medulloblastoma is the most common primary malignant central nervous system tumor arising in childhood. Survival rates for children with medulloblastomas have nearly doubled and so has the recognition that many survivors are impaired and new forms of treatment are needed. Its understanding and management represents both the progress and challenges…
Nothing is more frightening than to learn that your child has a brain tumor. These serious tumors are unfortunately all too common; in fact, malignant brain tumors are the most frequent type of solid cancer seen in childhood. To make matters more difficult, conventional radiation therapy - a mainstay of…
Children and adolescents who have undergone treatment for brain tumors may be more likely to exhibit behavior problems than their peers. There have been relatively few formal studies of this issue, and behavior problems have often not been included in studies of neuropsychological outcome following treatment. Studies which have been…
Cerebellar mutism was first reported in 1979 by Hirsh after a posterior fossa tumor resection. In the past, cerebellar mutism was thought to be an uncommon problem. However, there have been increasing numbers of case reports and literature reviews that indicate that cerebellar mutism may be significantly more common than…
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