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Vassar alumna Michelle Monje '98 talks about her work as a pediatric oncologist and her groundbreaking research on diffuse intrinsic pontine glioma, a highly aggressive pediatric brain tumor.

The Childhood Brain Tumor Foundation is thrilled to bring you two educational webcasts..

Medulloblastoma: A webcast presented by Dr. Roger J. Packer, Children's National Medical Center


December 27, 2007

To view and listen to the webcast, first open the slide presentation (requires Microsoft Powerpoint): Medulloblastoma.ppt

Then download and play the audio file: Medullablastoma.mp3

As you hear Dr. Packer say "next slide", click on the slide presentation to advance to the next slide.

Presented by The Childhood Brain Tumor Foundation and the Children's Brain Tumor Foundation

Late Effects in Childhood Cancer Survivors: A webcast presented by Dr. Paul Graham Fisher, Director of the Pediatric Neuro-Oncology Clinic at Lucile Salter Packard Children's Hospital at Stanford

paul fisher Kid

January 9, 2009

To view and listen to the webcast, click on the following link:
Late effects in Childhood Cancer Survivors
(Please wait a few seconds for the webcast to begin)

Presented by The Childhood Brain Tumor Foundation

Children's Brain Tumor Foundation and Childhood Brain Tumor Foundation are thrilled to work collaboratively to bring you an educational webcast series..

Making the Diagnosis
Presented by:
Peter C. Burger, M.D.
Johns Hopkins University
School of Medicine

Peter Burger Photo copy
The following is an outline of Dr. Burger's presentation.
You may find it helpful to follow along with this document during his lecture.

[Word] [pdf]

Astrocytoma: New Treatment Advances
Presented by:
Roger J. Packer, M.D.
Children's National
Medical Center

Roger Packer Photo
The following is an outline of Dr. Packer's presentation.
You may find it helpful to follow along with this document during his lecture.

[Word] [pdf]

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Mr. James Young, one of the Founding Board Members, is the longstanding Treasurer of the Childhood Brain Tumor Foundation, Inc. His son is a long-term brain tumor survivor, diagnosed in 1991. Mr. Young is grateful that his son, Bryan, has beat the odds and remained stable with a low-grade tumor that was very diffuse at diagnosis and was expected to recur every couple of years. Mr. Young’s dedication to the Foundation has been outstanding. He lends his support to all of CBTF’s local fund-raisers and activities. Mr. Young maintains all Foundation equipment and attends closely to accounting details, reports to the Board, and provides fiscal detail that empowers the Board to make well-informed decisions. Each year, Mr. Young is the direct interface with the auditor and conveys the budget and finance outcome to the Board of Directors.


Orbital Sciences Corporation – Senior Principal Aerospace Engineer


Education: B.S., Electrical Engineering

Carol Cornman, Vice President of the Childhood Brain Tumor Foundation, brings her leadership skills to the organization. Each year family, friends, and supporters join Carol and her daughters in celebrating the memory of her husband Geoff Cornman, a victim of a brain tumor many years ago. Carol brings to the Childhood Brain Tumor Foundation her years of experience as one of the owners of PRISM and Vice President of Business Development. With over 18 years of experience in delivery, business development, sales, operations and executive leadership, she maintains the ability to build and execute strategic business plans and teams that are centered on quality and deliver maximum results. A focus on quality is what allows Carol to provide services which exceed customer and employee expectations. Her consultant creativity coupled with her epic business ability ensures that she is called on to master superior success with any challenge faced.

Dr. Warren received her B.S., in medical technology in 1982 and her M.D., from Tufts University School of Medicine in 1990. She completed a residency in pediatrics at Children's National Medical Center, followed by a fellowship in pediatric oncology at the National Cancer Institute. She is board certified in pediatric hematology/oncology. Her research interests include performance of clinical trials, particularly in children with tumors of the central nervous system, non-invasive evaluation/imaging of the brain, and neurotoxicity resulting from tumors and their treatment.

Cancer of the central nervous system (CNS) is the leading cause of death from solid tumors in the pediatric population. For some types of CNS malignancies, such as diffuse intrinsic pontine glioma (DIPG) and recurrent malignant glioma, no significant improvement in survival has been demonstrated over the past three decades. The approach to treatment has not changed substantially, despite increasing knowledge of tumor biology. The goal of Dr. Warren's research is to establish new therapeutic paradigms based on pharmacokinetic and biologic rationale to improve both survival and quality of life for children with CNS tumors.

Dr. Warren's strategy entails a multifaceted approach.

  1. Experimental therapeutics and extensive noninvasive analysis of individual patients, including multiparametric imaging
  2. Utilization of a nonhuman primate model to study CNS pharmacology of agents and alternate delivery methods
  3. Identification of intratumor genomic alterations that encode potentially druggable targets

Click here to view Dr. Warren's full biography.

Associate Professor Pediatrics
Director, Pediatric Neuro-Oncology Program

Following his training in pediatrics, pediatric hematology-oncology and neuro-oncology, Dr. MacDonald has built a career that encompasses clinical, basic and translational research of childhood brain tumors. He has received continuous NIH-sponsored funding support for his research efforts for the past 9 years, which has focused on identification of molecular therapeutic targets of perdiatric brain tumors. Having pioneered the use of microarray technology for the study of pediatric medulloblastoma and astrocytoma, and discovering that the platelet-derived growth factor receptor (PDGFR) is active and over-produced by metastatic tumors and tumors demonstrating more malignant characteristics, respectively, he is now working to translate these and other novel findings to innovative treatments for children with brain tumors.

Before joining the Aflac Cancer Center to direct the Pediatric Neuro-Oncology Program in September 2009, Dr. MacDonald served as the Clinical Director of Neuro-oncology at Children’s National Medical Center from 1998-2009 and served as Chair of Infant Brain Tumors for the NIH-sponsored Pediatric Brain Tumor Consortium (PBTC) as well as Co-Chair of the PBTC Biology and Angiogenesis Committees since the group’s inception in 1999. In addition to serving on numerous clinical trial committees within PBTC and the Children’s Oncology Group, most prominently as Principal Investigator of the completed Phase I and currently ongoing Phase II study of cilengitide, which he helped to develop from bench-to-bedside, Dr. MacDonald was the institutional Principal Investigator for over 26 clinical trials conducted through PBTC.

One of his additional passions is training the next generation of pediatric scientists, and over the past 10 years, he has mentored 14 students, from undergraduate to graduate and medical, and 9 post-doctoral fellows, the majority of which are now currently conducting oncology research of their own.

Click here to view Dr. MacDonald's full biography.

Mrs. Young is the President and one of the Founding members of the Childhood Brain Tumor Foundation, an all-volunteer nonprofit organization founded in 1994 dedicated to supporting research, heightening awareness, and improving the quality of life for children affected by brain tumors. Her dedication to the cause comes from many cancer-related challenges her family has faced. At the age of 17 she lost her father to brain cancer. Her son is a long-term brain tumor survivor. She has taken these tragedies and turned her efforts to helping others in this situation through patient advocacy, awareness, and support for childhood brain tumor victims and their families.

Mrs. Young has served as a patient advocate, board member, and in various other roles in a number of related organizations, including:

  • Patient Advocate Steering Committee (2011 to present)
  • Patient Advocate Reviewer – Department of Defense, Peer Review Cancer Related Program (PRCRP) (2009 to present)
  • Patient Advocate – Children’s Oncology Group (COG) Developmental Therapeutics Steering Committee (2007 to present)
  • Patient Advocate – National Cancer Institute (NCI) Clinical Imaging Steering Committee (2011 to present)
  • Consumer Advocate in Research and Related Activities – NCI Special Emphasis Panels and Specialized Panel of Research Excellence (2000 to present)
  • Member, Central Institutional Review Board, Pediatrics (2009 to present)
  • Member, NCI Safety Monitoring Committee (2007 to present)
  • Member, American Brain Coalition (2009 to present)
  • Patient Advocate--National Cancer Institute Sub-Committee D (2004 to 2006)
  • Committee Member - Pediatric Brain Tumor Consortium Parent/Family Committee (2004 to present)
  • Board Member - Pediatric Brain Tumor Consoritum Foundation (2007 to present)
  • North American Brain Tumor Coalition (2001 to 2008, various roles, Secretary, Vice Chair, and last as Co-Chair)
  • National Institutes of Health/National Cancer Institute--Brain Tumor Progress Review Group, participant (2000)


University of Maryland, BA, Arts/Psychology
International Symposium on Pediatric Neuro-Oncology, 1998 to Present
Society for Neuro-Oncology, 2000 – 2008, 2012 to present


MCPS Educational Foundation, Inc. - Program Administrator (part-time)

Paul Graham Fisher is Professor of Neurology and Pediatrics, and by courtesy, Neurosurgery and Human Biology; the Beirne Family Professor of Pediatric Neuro-Oncology; and Division Chief of Child Neurology at Stanford University. He is also the Director of the Center for Brain and Behavior.

After starting his career on the faculty at Johns Hopkins, he was recruited back to Stanford in 1997 to Stanford, where he started the pediatric brain tumor program at Lucile Packard Children’s Hospital. That childhood brain tumor program is now the largest comprehensive childhood brain tumor center for research and care in the Western United States, and a member of the NCI’s Pediatric Brain Tumor Consortium. Professor Fisher is a nationally sought teacher, and in 2007 received both the 44th Annual Arthur L. Bloomfield Award and 39th Annual Henry J. Kaiser Family Foundation Award for excellence in teaching at the Stanford School of Medicine. At Stanford he also directs the undergraduate class “Cancer Epidemiology” in Human Biology. He is the Child Neurology Residency Director at the School of Medicine, Chair of the Section for Neurology in the American Academy of Pediatrics, and editorial board member for The Journal of Pediatrics and Journal of Neuro-Oncology, and previously Journal of Clinical Oncology. He is also a member of the Board of Directors for the National Brain Tumor Society and the Advisory Board for the Greater Bay Area Make-A-Wish Foundation.

His research focuses on epidemiology, therapy, and late effects of childhood brain tumors, and he has authored over 120 publications on brain tumors and other neurology topics. His epidemiologic work explores biologic underpinnings of childhood brain tumors, particularly medulloblastoma, ependymoma, and germ cell tumors.

His personal interests are his wife and three children, along with skiing, travel, gardening, bad golf, and anything baseball.

Academic History:

B.A., with Distinction, Stanford University, 1985
M.D., University of California, San Francisco, 1989
M.H.S., Johns Hopkins University, 1995

Paul G. Fisher, M.D. is a member of the Childhood Brain Tumor Foundation’s Medical/Scientific Advisory.

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